Black esophagus: a syndrome of acute esophageal necrosis associated with active alcohol drinking.
Anees SiddiqiFizah S ChaudharyHaider A NaqviNahar SalehRehan FarooqiMuhammad Nadeem YousafPublished in: BMJ open gastroenterology (2021)
Black esophagus, also known as acute esophageal necrosis (AEN) syndrome, is a rare entity characterized by patchy or diffuse circumferential black pigmentation of the esophageal mucosa from ischemic necrosis. It may present with life-threatening upper gastrointestinal hemorrhage resulting in high mortality in immunocompromised patients. Advanced age with multiple comorbidities compounded with compromised hemodynamic states are poor prognostic factors. Findings on laboratory work-up and radiological imaging are non-specific. After initial resuscitation, endoscopic evaluation and histological examination of esophageal biopsy are diagnostic. Early recognition and aggressive resuscitation are the fundamental principles for the management of AEN and better outcome of the disease. We report a case of a 56-year-old woman with diabetes mellitus, gastro-esophageal reflux disease, and active alcohol binging who presented with hematemesis and acute epigastric pain due to AEN. This case illustrates a rare etiology of AEN due to active alcohol drinking, which may be overlooked. Physician awareness about this etiology is important as early recognition and timely management may improve survival.
Keyphrases
- prognostic factors
- liver failure
- respiratory failure
- alcohol consumption
- cardiac arrest
- end stage renal disease
- drug induced
- aortic dissection
- chronic kidney disease
- primary care
- ejection fraction
- chronic pain
- emergency department
- newly diagnosed
- ultrasound guided
- hepatitis b virus
- case report
- neuropathic pain
- cardiovascular disease
- adipose tissue
- ischemia reperfusion injury
- septic shock
- cardiopulmonary resuscitation
- type diabetes
- insulin resistance
- mass spectrometry
- metabolic syndrome
- extracorporeal membrane oxygenation
- photodynamic therapy
- coronary artery disease
- acute respiratory distress syndrome
- skeletal muscle
- subarachnoid hemorrhage