Sequential introduction of a multistep testing algorithm and nucleic acid amplification testing leading to an increase in Clostridioides difficile detection and a trend toward increased strain diversity.
Andrew M SkinnerBrian YuAdam CheknisSusan M PachecoDale N GerdingStuart JohnsonPublished in: Infection control and hospital epidemiology (2020)
MST and NAAT had similar detection rates for C. difficile. Compared to toxin testing alone, they detected increased diversity of C. difficile strains, many of which were low toxin producing.