The function of Piezo1 in colon cancer metastasis and its potential regulatory mechanism.

Yanhua SunMing LiGuangjie LiuXue ZhangLianghui ZhiJing ZhaoGuiying Wang

Published in: Journal of cancer research and clinical oncology (2020)

In our study, Piezo1 is involved in colon cancer cell metastasis. Furthermore, our findings indicated a possible Piezo1-MCU-HIF-1α-VEGF axis, which still need further exploration.

Keyphrases

endothelial cells
transcription factor
vascular endothelial growth factor