Clinical features, therapeutic requirements and evolution of patients with Crohn's disease and upper gastrointestinal involvement (CROHNEX study).
Empar SainzYamile ZabanaIsabel MiguelAgnès Fernández-ClotetBelén BeltránLaura NúñezMaría José GarcíaMaría Dolores Martín-ArranzEva IglesiasFiorella CañeteAna GutiérrezMarta PiquerasIsabel Pérez-MartínezLuis BujandaIago Rodriguez-LagoMaría José CasanovaPablo NavarroRaquel VicenteOlga MerinoAlicia AlgabaCristina RodríguezJosé M HuguetFernando Fernández-BañaresEugeni DomènechMaria Estevenull nullPublished in: Alimentary pharmacology & therapeutics (2021)
The largest cohort of patients with CD and UGI provides information on the natural history of this particular phenotype. Increased awareness of the clinical picture and therapeutic requirements of these patients could lead to earlier diagnosis and treatment of upper gastrointestinal lesions, preventing the structural damage frequently seen in these patients at diagnosis and during follow-up.