Amelioration of oxidative stress, cholinergic dysfunction, and neuroinflammation in scopolamine-induced amnesic rats fed with pomegranate seed.

Mahsan AkbarianFarshad MirzaviSabiheh AmirahmadiMahmoud HosseiniMohsen AlipourHadi FeiziArezoo Rajabian

Published in: Inflammopharmacology (2022)

PSE successfully alleviated scopolamine-induced memory and learning deficits in rats which is probably via modulating cholinergic system function, oxidative stress, and inflammatory cytokines.

Keyphrases

oxidative stress
diabetic rats
high glucose
traumatic brain injury
dna damage
ischemia reperfusion injury
signaling pathway
induced apoptosis
drug induced
working memory
inflammatory response
heat shock protein