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Effects of empagliflozin on markers of liver steatosis and fibrosis and their relationship to cardiorenal outcomes.

Sabine KahlAnne Pernille OfstadBernard ZinmanChristoph WannerElke SchuelerNaveed SattarCatherine M ViscoliMichael Roden
Published in: Diabetes, obesity & metabolism (2022)
Empagliflozin may reduce steatosis but not fibrosis risk in individuals with type 2 diabetes and cardiovascular disease. The improvements in cardiorenal outcomes and mortality associated with empagliflozin therapy appear to be independent of steatosis and fibrosis risk.
Keyphrases
  • insulin resistance
  • cardiovascular disease
  • high fat diet
  • high fat diet induced
  • type diabetes
  • liver fibrosis
  • cardiovascular risk factors