Immune checkpoint inhibitor treatment does not impair ovarian or endocrine function in a mouse model of triple negative breast cancer.

Payton De La CruzMorgan F Woodman-SousaJulia N McAdamsEllia SweeneyLola HakimMelanie Morales AquinoKathryn J Grive

Published in: bioRxiv : the preprint server for biology (2024)

Taken together, our results suggest that immunotherapy may be a promising component of fertility-sparing therapeutic regimens for patients that wish to retain ovarian and endocrine function after cancer treatment.

Keyphrases

mouse model
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
combination therapy