Accuracy of Calcium Scoring calculated from contrast-enhanced Coronary Computed Tomography Angiography using a dual-layer spectral CT: A comparison of Calcium Scoring from real and virtual non-contrast data.
Jonathan NadjiriGeorgios KaissisFelix MeurerFlorian WeisKarl-Ludwig LaugwitzAlexandra S StraeterDaniela MuenzelPeter B NoëlErnst J RummenyMichael RasperPublished in: PloS one (2018)
Determination of Calcium Score from contrast enhanced CCTA using spectral imaging with a dual-layer detector is feasible and shows good agreement with the conventional technique when a proportionality factor is applied. The observed difference between both methods is due to an underestimation of plaque volume, and-to an even greater extend -an underestimation of plaque density with the virtual non-contrast approach. Our data suggest that radiation exposure can be reduced through omitting additional native scans for patients referred to CCTA when using a dual-layer spectral system without the usual limitations of dual energy analysis.
Keyphrases
- contrast enhanced
- dual energy
- image quality
- computed tomography
- diffusion weighted
- magnetic resonance imaging
- magnetic resonance
- coronary artery disease
- diffusion weighted imaging
- end stage renal disease
- coronary artery
- electronic health record
- newly diagnosed
- peritoneal dialysis
- positron emission tomography
- ejection fraction
- high resolution
- big data
- patient reported outcomes
- prognostic factors
- data analysis
- heart failure
- aortic valve
- transcatheter aortic valve replacement
- aortic stenosis
- photodynamic therapy
- pet ct
- solid phase extraction