Benefits of perioperative sildenafil therapy in children with a ventricular septal defect with pulmonary artery hypertension on early surgical outcomes.
Ruchit PatelShyam Kumar Singh ThingnamAnand Kumar MishraManoj Kumar RohitVinay UpadhyayVikram HalderVidur BansalPublished in: Journal of cardiac surgery (2020)
Oral Sildenafil therapy is an inexpensive and well-tolerated method for reducing pulmonary hypertension secondary to non-restrictive ventricular septal defect. It has noteworthy advantages regarding early surgical outcomes like reduced cardiopulmonary bypass time, improved mechanical ventilation time, lower inotrope requirement and shorter hospital stay if used preoperatively in select patient population.
Keyphrases
- pulmonary hypertension
- pulmonary artery
- pulmonary arterial hypertension
- mechanical ventilation
- heart failure
- coronary artery
- left ventricular
- intensive care unit
- acute respiratory distress syndrome
- blood pressure
- young adults
- healthcare
- catheter ablation
- emergency department
- stem cells
- cardiac surgery
- respiratory failure
- acute kidney injury
- adverse drug
- electronic health record
- smoking cessation