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Modeling photoplethysmographic signals in camera-based perfusion measurements: optoelectronic skin phantom.

Michael PaulAna Filipa MotaChristoph Hoog AntinkVladimir BlazekSteffen Leonhardt
Published in: Biomedical optics express (2019)
The remote acquisition of photoplethysmographic (PPG) signals via a video camera, also known as photoplethysmography imaging (PPGI), is not yet standardized. In general, PPGI is investigated with test persons in a laboratory setting. While these in-vivo tests have the advantage of generating real-life data, they suffer from the lack of repeatability and are comparatively effort-intensive because human subjects are required. Consequently, studying changes in signal morphology, for example, due to aging or pathological effects, is practically impossible. As a tool to study these effects, a hardware PPG simulator has been developed: this is a phantom which simulates and generates both 1D and locally resolved 2D optical PPG signals. Here, we demonstrate that it is possible to generate PPG-like signals with various signal morphologies by means of a purely optoelectronic setup, namely an LED array, and to analyze them by means of PPGI. Signals extracted via a camera show good agreement with simulated generated signals. In fact, the first phantom design is suitable to demonstrate this qualitatively.
Keyphrases
  • high resolution
  • high speed
  • endothelial cells
  • convolutional neural network
  • image quality
  • computed tomography
  • machine learning
  • mass spectrometry
  • photodynamic therapy