Chronic Liquid Fructose, but not Glucose, Supplementation Selectively Induces Visceral Adipose Tissue Leptin Resistance and Hypertrophy in Female Sprague-Dawley Rats.
Gemma SangüesaNúria RoglansJosé Carlos MontañésMiguel BaenaAna Magdalena VelázquezRosa María SánchezMarta AlegretJuan Carlos LagunaPublished in: Molecular nutrition & food research (2018)
Chronic consumption of fructose places a greater burden on metabolic homeostasis than equivalent consumption of glucose, inducing hyperleptinemia, generalized leptin resistance, and increased body weight due to expanded, hypertrophic vWAT.