Serum keratin 19 (CYFRA21-1) is a prognostic biomarker in severe alcoholic hepatitis.
Stephen Rahul AtkinsonMahmoud AlyKatharina RemihLuke David TysonNurdan GuldikenRobert GoldinAlberto QuagliaMark R ThurszPavel StrnadPublished in: Liver international : official journal of the International Association for the Study of the Liver (2022)
In sAH serum, CYFRA21-1 levels associate with the presence of ASH on biopsy and independently predict 90-day survival. As a single marker performance is comparable to established scoring systems. Therefore, CYFRA21-1, which is available in many clinical laboratories, may become a useful component of prognostic models.