Amyotrophic lateral sclerosis type 8 is not a pure motor disease: evidence from a neuropsychological and behavioural study.

Cássia de AlcântaraMarcelo Maroco CruzeiroMarcondes C FrançaSarah Teixeira CamargosLeonardo Cruz de Souza

Published in: Journal of neurology (2019)

ALS8 patients present mild executive dysfunction and behavioural changes such as mood disorders, apathy and stereotypic behaviour. Our findings suggest that ALS8 is not a pure motor disorder and it is associated with subtle cognitive and behavioural impairments.

Keyphrases

amyotrophic lateral sclerosis
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
oxidative stress
patient reported outcomes
mild cognitive impairment
working memory
sleep quality