PERK-Dependent Activation of the JAK2/STAT3 Pathway Contributes to High Glucose-Induced Extracellular Matrix Deposition in Renal Tubular Epithelial Cells.

Published in: International journal of endocrinology (2021)

Our data indicated that the ECM accumulation induced by high glucose arouse via the PERK-dependent JAK2/STAT3-signaling pathway in renal tubular epithelial cells.

Keyphrases

high glucose
extracellular matrix
endothelial cells
signaling pathway
endoplasmic reticulum stress
induced apoptosis
electronic health record
big data
machine learning
oxidative stress
deep learning