Changes in Anticoagulation Practice in Subjects Admitted with Stroke Associated with Atrial Fibrillation, following introduction of Direct Oral Anticoagulants over 2013-2021.
Joseph A HarbisonJoan McCormackOlga BrychRonan CollinsNiamh O'ConnellMary RandlesCormac KennedyPeter J KellyTim CassidyPublished in: International journal of stroke : official journal of the International Stroke Society (2023)
DOACs have led to increased use of anticoagulation but Warfarin use fell by two thirds. There has been a reduction in the proportion of AF associated IS without a noticeable increase in intracerebral haemorrhage. Increased anticoagulation correlated with reduced numbers of strokes in those >80 years, and in the proportion of patients thrombolysed.
Keyphrases
- atrial fibrillation
- direct oral anticoagulants
- oral anticoagulants
- venous thromboembolism
- catheter ablation
- left atrial
- left atrial appendage
- end stage renal disease
- heart failure
- percutaneous coronary intervention
- ejection fraction
- chronic kidney disease
- newly diagnosed
- primary care
- healthcare
- prognostic factors
- peritoneal dialysis
- coronary artery disease
- acute coronary syndrome
- blood brain barrier
- quality improvement