Lung Cancer Surgery in Octogenarians: Implications and Advantages of Artificial Intelligence in the Preoperative Assessment.
Massimiliano BassiRita Vaz SousaBeatrice ZacchiniAnastasia CentofantiFrancesco FerranteCamilla PoggiCarolina CarilloYlenia PecoraroDavide AmoreDaniele DisoMarco AnileTiziano De GiacomoFederico VenutaJacopo VannucciPublished in: Healthcare (Basel, Switzerland) (2024)
The general world population is aging and patients are often diagnosed with early-stage lung cancer at an advanced age. Several studies have shown that age is not itself a contraindication for lung cancer surgery, and therefore, more and more octogenarians with early-stage lung cancer are undergoing surgery with curative intent. However, octogenarians present some peculiarities that make surgical treatment more challenging, so an accurate preoperative selection is mandatory. In recent years, new artificial intelligence techniques have spread worldwide in the diagnosis, treatment, and therapy of lung cancer, with increasing clinical applications. However, there is still no evidence coming out from trials specifically designed to assess the potential of artificial intelligence in the preoperative evaluation of octogenarian patients. The aim of this narrative review is to investigate, through the analysis of the available international literature, the advantages and implications that these tools may have in the preoperative assessment of this particular category of frail patients. In fact, these tools could represent an important support in the decision-making process, especially in octogenarian patients in whom the diagnostic and therapeutic options are often questionable. However, these technologies are still developing, and a strict human-led process is mandatory.
Keyphrases
- artificial intelligence
- end stage renal disease
- early stage
- chronic kidney disease
- ejection fraction
- machine learning
- newly diagnosed
- minimally invasive
- deep learning
- prognostic factors
- peritoneal dialysis
- patients undergoing
- endothelial cells
- patient reported outcomes
- coronary artery disease
- stem cells
- mesenchymal stem cells
- mass spectrometry
- radiation therapy
- bone marrow
- rectal cancer
- percutaneous coronary intervention
- acute coronary syndrome
- lymph node
- locally advanced
- clinical evaluation