Suppressing STAT3 activation impairs bone formation during maxillary expansion and relapse.

Xiaoyue XiaoJianwei ChenQiming ZhaiLiangjing XinXinhui ZhengSi Wang Jinglin Song

Published in: Journal of applied oral science : revista FOB (2023)

STAT3 inactivation reduced osteoblast-mediated bone formation during palatal expansion and post-expansion relapse, thus it may be a potential therapeutic target to treat force-induced bone formation.

Keyphrases

cell proliferation
free survival
diabetic rats
high glucose
signaling pathway
oxidative stress
endothelial cells
drug induced