Antibody Mediated Rejection is not Associated with Worse Survival in Adherent Heart Transplant Patients in the Contemporary Era.

Paul J Kim Vincenzo Cusi Ashley Cardenas Yuko Tada Florin Vaida Nicholas Wettersten Jennifer Chak Priyesha Bijlani Victor G Pretorius Marcus Anthony Urey Gerald P Morris Grace Lin

Published in: medRxiv : the preprint server for health sciences (2023)

Medically adherent C4d+/DSA+ HTx patients show significantly greater risk for cardiac allograft dysfunction but not cardiac mortality or retransplant. In contrast, C4d+/DSA- patients represent a new immunopathologic group with a clinical course similar to that of HTx patients without antibody mediated rejection.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
heart failure
cardiovascular disease
oxidative stress
computed tomography
left ventricular
patient reported outcomes
atrial fibrillation