Innovative experimental animal models for real-time comparison of antithrombogenicity between two oxygenators using dual extracorporeal circulation circuits and indocyanine green fluorescence imaging.

Hironobu Sakurai Tatsuki FujiwaraKatsuhiro OhuchiWataru Hijikata Yusuke Inoue Osamu MaruyamaTomoki TaharaSachie YokotaYui TanakaYoshiaki TakewaTomohiro MizunoHirokuni Arai

Published in: Artificial organs (2022)

We devised an innovative experimental animal model for comparison of antithrombogenicity in ECMO circuits. This model enabled simultaneous evaluation of two different ECMO circuits under the same biological conditions and reduced the number of sacrificed experimental animals.

Keyphrases

fluorescence imaging
extracorporeal membrane oxygenation
acute respiratory distress syndrome
photodynamic therapy
intensive care unit
mechanical ventilation