Brain structure, IQ, and psychopathology in young offspring of patients with schizophrenia or bipolar disorder.
Neeltje E M van HarenNikita SetiamanMartijn G J C KoevoetsHeleen BaalbergenRene S KahnManon H J HillegersPublished in: European psychiatry : the journal of the Association of European Psychiatrists (2020)
Despite sharing a lower IQ and a higher prevalence of psychiatric disorders, brain abnormalities in BDo appear less pronounced (but are not absent) than in SZo. Lower ICV in SZo implies that familial risk for schizophrenia has a stronger association with stunted early brain development than familial risk for bipolar disorder.