Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: a systematic review and meta-analysis.

Gemma E CurrieAlison H M TaylorToshiro FujitaHiroshi OhtsuMorten LindhardtPeter RossingLene BoesbyNicola C EdwardsCharles J FerroJonathan N TownendAnton H van den MeirackerMohammad G SaklayenSonia OveisiAlan G JardineChristian DellesDavid J PreissPatrick B Mark

Published in: BMC nephrology (2016)

Mineralocorticoid receptor antagonism reduces blood pressure and urinary protein/albumin excretion with a quantifiable risk of hyperkalaemia above predefined study upper limit.

Keyphrases

chronic kidney disease
blood pressure
end stage renal disease
heart rate
binding protein
hypertensive patients
type diabetes
adipose tissue
insulin resistance
small molecule