High burden of clonal mast cell disorders and hereditary α-tryptasemia in patients who need Hymenoptera venom immunotherapy.
Peter KorosecGunter Johannes SturmJonathan J LyonsTinkara Pirc MaroltManca SvetinaKosnik MitjaMihaela ZidarnMark KačarNina FrelihNika LalekAjda Demšar LuzarSamo ZverMatevž ŠkergetEwa CzarnobilskaWojciech DygaSanja Popović GrleMiroslav SamarzijaLisa Arzt-GradwohlUrban ČerpesGrzegorz PorebskiBranko PevecEva SchadelbauerPeter KopačJulij ŠelbMatija RijavecPublished in: Allergy (2024)
By employing prospective universal tryptase genotyping and examination for KIT p.D816V in PBL in large HVA populations, we have demonstrated a high burden of clonal MC disorders and HαT in patients who require VIT.