Inorganic nitrate benefits contrast-induced nephropathy after coronary angiography for acute coronary syndromes: the NITRATE-CIN trial.

Daniel A JonesAnne-Marie BeirneMatthew KelhamLucinda WynneMervyn AndiapenKrishnaraj S RathodTipparat ParakawJessica AdamsAnnastazia LearoydKamran KhanThomas GodecPaul WrightSotiris AntoniouAndrew WraggMuhammad YaqoobAnthony Mathur Amrita Ahluwalia

Published in: European heart journal (2024)

In patients at risk of renal injury undergoing coronary angiography for ACS, a short (5 day) course of once-daily inorganic nitrate reduced CIN, improved kidney outcomes at 3 months, and MACE events at 1 year compared to placebo.

Keyphrases

acute coronary syndrome
nitric oxide
drinking water
phase iii
percutaneous coronary intervention
magnetic resonance
antiplatelet therapy
clinical trial
high glucose
diabetic rats
physical activity
water soluble
phase ii
oxidative stress
adipose tissue
perovskite solar cells
computed tomography
contrast enhanced