Fixation of polyvinylidene fluoride (PVDF) mesh with cyanoacrylate-derived glues in a rat experimental model: histopathologic immunohistochemical and morphometric study.
Alessandro PoliF ParisiF MillantaL SolfanelliP García-PastorC MagliaroV MiragliottaS BurchielliPublished in: Hernia : the journal of hernias and abdominal wall surgery (2019)
Our study confirmed that CA tissue adhesives induced the good incorporation of prosthetic mesh within host tissue with a low incidence of complications and reduced acute tissue reaction. At 30 days post-surgery no signs of mesh disinsertion or migration were observed, the prosthetic mesh adhesion was due to the presence of a dense mature connective tissue rich in type I collagen fibres.