Antagonistic effects of mitochondrial matrix and intermembrane space proteases on yeast aging.

Montserrat VegaDavid CastilloLaura de CubasYirong WangYing HuangElena HidalgoMargarita Cabrera

Published in: BMC biology (2022)

Our characterization of the mitochondrial protease mutants demonstrates that mitophagy sustains the lifespan extension of long-lived mutants displaying a higher respiration potential.

Keyphrases

oxidative stress
wild type
saccharomyces cerevisiae
human health
climate change