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The apoptotic effects of progesterone on breast cancer (MCF-7) and human osteosarcoma (MG-636) cells.

H R MotamedM ShariatiRahim AhmadiS KhatamsazM Mokhtari
Published in: Physiology international (2020)
The cytotoxic effect of progesterone on breast cancer and osteosarcoma cells was mediated by apoptotic pathways. In this context, progesterone triggers the extrinsic and intrinsic apoptotic pathways in MCF-7 cells and induces the intrinsic apoptotic pathway in MG-63 cells.
Keyphrases
  • induced apoptosis
  • cell death
  • cell cycle arrest
  • endoplasmic reticulum stress
  • endothelial cells
  • anti inflammatory
  • breast cancer cells
  • estrogen receptor
  • pi k akt
  • young adults
  • breast cancer risk
  • childhood cancer