Aberrant DNA methylation is associated with aggressive clinicopathological features and poor survival in cutaneous melanoma.
B de Unamuno BustosR Murria EstalG Pérez SimóJ Simarro FarinosC Pujol MarcoM Navarro MiraV Alegre de MiquelR Ballester SánchezV Sabater MarcoM Llavador RosSarai Palanca SuelaR Botella EstradaPublished in: The British journal of dermatology (2018)
Aberrant methylation of TSGs is a frequent event in melanoma. It is associated with aggressive clinicopathological features and poorer survival. Epigenetic alterations may represent a significant prognostic marker with utility in routine practice.