Association of aPTT-Guided Anticoagulation Monitoring with Thromboembolic Events in Patients Receiving V-A ECMO Support: A Systematic Review and Meta-Analysis.

Zoran BukumiricRobert BreitkopfBenedikt TremlDragana JadzicChristoph OberleitnerUlvi Cenk OezpekerNicole InnerhoferZoran Bukumiric

Published in: Journal of clinical medicine (2023)

Despite the tremendous development of critical care, aPTT-guided systemic anticoagulation is still the standard monitoring tool. We did not find any association of aPTT levels with thrombosis. Further evidence and new trials should clarify the true incidence of thromboembolic events, along with the best anticoagulation and monitoring strategy in veno-arterial ECMO patients.

Keyphrases

atrial fibrillation
extracorporeal membrane oxygenation
venous thromboembolism
acute respiratory distress syndrome
end stage renal disease
ejection fraction
respiratory failure
risk factors
pulmonary embolism
intensive care unit
patient reported