Management of Coronary Disease in Patients with Advanced Kidney Disease.
Sripal BangaloreDavid J MaronSean M O'BrienJerome L FlegEvgeny I KretovCarlo BriguoriUpendra KaulHarmony R ReynoldsTomasz MazurekMandeep S SidhuJeffrey S BergerRoy O MathewOlga BockeriaSamuel BroderickRadoslaw PracońCharles A HerzogZhen HuangGregg W StoneWilliam E BodenJonathan D NewmanZiad A AliDaniel B MarkJohn A SpertusKaren P AlexanderBernard R ChaitmanGlenn M ChertowJudith S Hochmannull nullPublished in: The New England journal of medicine (2020)
Among patients with stable coronary disease, advanced chronic kidney disease, and moderate or severe ischemia, we did not find evidence that an initial invasive strategy, as compared with an initial conservative strategy, reduced the risk of death or nonfatal myocardial infarction. (Funded by the National Heart, Lung, and Blood Institute and others; ISCHEMIA-CKD ClinicalTrials.gov number, NCT01985360.).