Inosine induces acute hyperuricaemia in rhesus monkey (Macaca mulatta) as a potential disease animal model.

Dong-Hong TangChen-Yun WangXi HuangHong-Kun YiZhe-Li LiKai-Li MaYou-Song YeJian-Wen Zhang

Published in: Pharmaceutical biology (2021)

An acute HUA animal model with high reproducibility was induced; it can be applied to evaluate new anti-HUA drugs in vivo and explore the disease pathogenesis.

Keyphrases

drug induced
liver failure
respiratory failure
aortic dissection
high glucose
hepatitis b virus
diabetic rats
intensive care unit