Propensity score-matched analysis of systemic chemotherapy versus salvage hysterectomy for persistent cervical cancer after definitive radiotherapy/concurrent chemoradiotherapy.
Munetaka TakekumaFumiaki TakahashiSeiji MabuchiWataru KudakaKoji HorieMariko IkedaAyumi ShikamaAkira MitsuhashiShoji NagaoShiro SuzukiMika MizunoShin NishioHideki TokunagaYukinobu OtaTakahiro KasamatsuRyo KitagawaTakafumi ToitaHiroaki KobayashiMitsuya IshikawaNobuo YaegashiPublished in: BMC cancer (2020)
The current study demonstrated that, when compared to systemic CT, the adoption of salvage HT for patients with persistent cervical cancer after definitive RT/CCRT reduced mortality rate by about 60%. This indicates that salvage HT could be curative treatment for those patients. Further prospective clinical trials with regard to salvage HT after RT/CCRT are warranted.
Keyphrases
- locally advanced
- rectal cancer
- clinical trial
- squamous cell carcinoma
- radiation therapy
- end stage renal disease
- prognostic factors
- ejection fraction
- chronic kidney disease
- computed tomography
- early stage
- type diabetes
- cardiovascular disease
- peritoneal dialysis
- magnetic resonance imaging
- electronic health record
- drug induced
- pet ct