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Invasive vs. conservative management of older patients with non-ST-elevation acute coronary syndrome: individual patient data meta-analysis.

Christos P KotanidisGregory B MillsBjørn BendzErlend S BergDavid Hildick-SmithGeir HirlekarDejan MilasinovicNuccia MoriciAung MyatNicolai TegnJuan Sanchis ForésStefano SavonittoStefano De ServiKeith A A FoxStuart PocockVijay Kunadian
Published in: European heart journal (2024)
No evidence was found that routine invasive treatment for NSTEACS in older patients reduces the risk of a composite of all-cause mortality and MI within 1 year compared with conservative management. However, there is convincing evidence that invasive treatment significantly lowers the risk of repeat MI or urgent revascularisation. Further evidence is needed from ongoing larger clinical trials.
Keyphrases
  • acute coronary syndrome
  • systematic review
  • clinical trial
  • electronic health record
  • percutaneous coronary intervention
  • coronary artery disease
  • meta analyses
  • deep learning
  • smoking cessation
  • phase ii