Prognostic Value of the PARIS Thrombotic Risk Score for 2-Year Mortality After Percutaneous Coronary Intervention.
Xueyan ZhaoJianxin LiXiaofang TangYing XianLin JiangJue ChenLijian GaoZhan GaoShubin QiaoYuejin YangRunlin GaoBo XuJin-Qing YuanPublished in: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis (2019)
The Patterns of non-Adherence to Anti-Platelet Regimen in Stented Patients (PARIS) thrombotic risk score is a novel score for predicting the risk of coronary thrombotic events after percutaneous coronary intervention (PCI). We assessed the prognostic value of this score for mortality in patients with PCI. In this prospective, observational study, we enrolled 10 724 consecutive patients underwent PCI. The primary end point was all-cause death and the secondary end point was major adverse cardiovascular and cerebrovascular events (MACCE) as a composite of all-cause death, myocardial infarction, revascularization, stent thrombosis, or stroke. Among 9782 patients without in-hospital events, a total of 97 deaths and 1002 MACCE occurred during the 2-year follow-up. The mortality risk of patients in the high-risk group was 2.31 times higher than that in the low-risk group (hazard ratio, 2.31; P = .001). This risk score showed prognostic value in evaluating mortality (area under the receiver operating characteristic curve [AUROC], 0.607; 95% confidence interval [CI], 0.551-0.663) and MACCE (AUROC, 0.544; 95% CI, 0.526-0.563; both P < .001). The prognostic value of mortality was higher than that of MACCE (Z = 2.09, P = .04). The PARIS thrombotic risk score shows modest prognostic value for mortality and MACCE, and the prognostic value of mortality is better than that of MACCE.
Keyphrases
- percutaneous coronary intervention
- coronary artery disease
- end stage renal disease
- cardiovascular events
- acute coronary syndrome
- acute myocardial infarction
- st segment elevation myocardial infarction
- ejection fraction
- chronic kidney disease
- atrial fibrillation
- newly diagnosed
- st elevation myocardial infarction
- coronary artery bypass grafting
- prognostic factors
- risk factors
- antiplatelet therapy
- peritoneal dialysis
- type diabetes
- healthcare
- coronary artery
- emergency department
- cardiovascular disease
- left ventricular
- heart failure
- electronic health record
- aortic stenosis
- acute care
- patient reported