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Somatosensory evoked potentials and magnetic resonance imaging of the central nervous system in early multiple sclerosis.

Alexander WuschekMatthias BussasMalek El HusseiniLaura HarabaczViktor PinekerViola PongratzAchim BertheleIsabelle RiedererClaus ZimmerBernhard HemmerJan S KirschkeMark Mühlau
Published in: Journal of neurology (2022)
Compared to tSSEP, SC MRI is the more sensitive diagnostic biomarker regarding SC involvement. In early MS, lesions as detectable by T2-weighted MRI are the main driver of abnormal tSSEP. However, tSSEP were more closely associated with disability, which is compatible with a potential role of tSSEP as prognostic biomarker in complementation of MRI.
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