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Proteomics approach for biomarker discovery in Kawasaki disease.

Rajni KumrahAnkur Kumar JindalDeepti SuriSurjit Singh
Published in: Expert review of clinical immunology (2024)
Efforts to improve the clinical and diagnostic evaluation of KD have focused on general markers of inflammation that are not specific for KD. Identification of a proteomic-based biomarker can reliably and specifically differentiate KD from other diseases and could help in the prompt diagnosis. Comprehensive analysis of the serum proteome of patients with KD may be helpful in identifying candidate protein biomarkers.
Keyphrases
  • oxidative stress
  • small molecule
  • mass spectrometry
  • high throughput
  • protein protein
  • quality improvement
  • binding protein
  • amino acid