Cont-ID: detection of sample cross-contamination in viral metagenomic data.

Published in: BMC biology (2023)

Cross-contamination between samples when detecting viruses using HTS (Illumina technology) can be monitored and highlighted by Cont-ID (provided an alien control is present). Cont-ID is based on a flexible methodology relying on the output of bioinformatics analyses of the sequencing reads and considering the contamination pattern specific to each batch of samples. The Cont-ID method is adaptable so that each laboratory can optimise it before its validation and routine use.

Keyphrases

risk assessment
drinking water
health risk
human health
sars cov
single cell
electronic health record
loop mediated isothermal amplification
big data
heavy metals
climate change
microbial community
antibiotic resistance genes
quantum dots
data analysis
high throughput sequencing