The Association of Blood Biomarkers and Body Mass Index in Knee Osteoarthritis: A Cross-Sectional Study.
Paul SchadlerBirgit LohbergerBettina ThauererMartin FaschingbauerWerner KullichMartin Helmut StradnerAndreas LeithnerValentin RitschlMaisa OmaraBibiane Steinecker-FrohnwieserPublished in: Cartilage (2022)
Our findings confirm studies on FABP4, leptin, and resistin with regard to obesity and the metabolic syndrome. There was no association of the investigated biomarkers with KOA severity, most likely due to the patient selection (end-stage KOA patients). Based on this absence of BMI-dependent changes in the metabolome, we might assume that BMI is not correlated with KOA severity in this specific patient group.
Keyphrases
- body mass index
- knee osteoarthritis
- metabolic syndrome
- weight gain
- end stage renal disease
- case report
- insulin resistance
- ejection fraction
- physical activity
- newly diagnosed
- chronic kidney disease
- type diabetes
- prognostic factors
- peritoneal dialysis
- weight loss
- cardiovascular disease
- risk factors
- uric acid
- cardiovascular risk factors
- patient reported outcomes
- high fat diet induced
- binding protein
- atomic force microscopy
- high resolution
- high speed
- case control