Global gene expression and chromatin accessibility of the peripheral nervous system in animal models of persistent pain.

Kimberly E StephensWeiqiang ZhouZachary RenfroZhicheng JiHongkai JiYun GuanSean D Taverna

Published in: Journal of neuroinflammation (2021)

Our improved understanding of the changes in chromatin accessibility that occur in chronic pain states may identify regulatory genomic elements that play essential roles in modulating gene expression in the DRG.

Keyphrases

gene expression
chronic pain
dna methylation
pain management
transcription factor
genome wide
signaling pathway
dna damage
copy number
spinal cord injury
neuropathic pain
chemotherapy induced