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Imatinib melylate as second-line treatment of bronchiolitis obliterans after allogenic hematopoietic stem cell transplantation in children.

Maura FaraciErica RicciFrancesca BagnascoFilomena PierriStefano GiardinoDonata GirosiRoberta OlceseElio CastagnolaGian Michele MagnanoEdoardo Lanino
Published in: Pediatric pulmonology (2020)
BO after HSCT in the pediatric population has a high incidence and mortality rate. In terms of overall response and tolerability, this study showed relevant improvements in the prognosis of children with BO after the introduction of IM. Further prospective studies among children are needed to confirm these results.
Keyphrases
  • young adults
  • risk factors
  • acute myeloid leukemia
  • type diabetes
  • cardiovascular events
  • study protocol
  • double blind
  • case control
  • respiratory syncytial virus
  • placebo controlled