Kinesin family member 23, regulated by FOXM1, promotes triple negative breast cancer progression via activating Wnt/β-catenin pathway.

Zhi LiHai-Yan YangXiao-Lan ZhangXu ZhangYu-Zhou HuangXin-Yuan DaiLiang ShiGuo-Ren ZhouJi-Fu WeiQiang Ding

Published in: Journal of experimental & clinical cancer research : CR (2022)

Our findings elucidate WDR5/FOXM1/KIF23/Wnt/β-catenin axis is associated with TNBC progression and may provide a novel and promising therapeutic target for TNBC treatment.

Keyphrases

cell proliferation
stem cells
signaling pathway
combination therapy
replacement therapy