Admission Clinical and EEG Features Associated With Mortality and Long-term Neurologic and Cognitive Outcomes in Pediatric Cerebral Malaria.
Daniel James ClarkCaitlin BondAlexander AndrewsDaniel J MullerAngela SarkisianRobert O OpokaRichard IdroPaul BangiranaAndy WittenNicholas J SausenGretchen L BirbeckChandy C JohnDouglas G PostelsPublished in: Neurology (2023)
In children with cerebral malaria, seizure number is strongly associated with risk of long-term neurologic deficits, while seizure number and specific EEG features (average background voltage, dominant rhythm frequency, presence of vertex sharp waves, presence of variability) are independently associated with cognitive outcomes. Future studies should evaluate the predictive value of these findings.
Keyphrases
- subarachnoid hemorrhage
- functional connectivity
- plasmodium falciparum
- working memory
- resting state
- young adults
- emergency department
- traumatic brain injury
- cardiovascular events
- atrial fibrillation
- risk factors
- heart rate
- type diabetes
- cerebral ischemia
- current status
- brain injury
- metabolic syndrome
- high density
- case control
- blood pressure
- blood brain barrier