Availability of evidence and comparative effectiveness for surgical versus drug interventions: an overview of systematic reviews and meta-analyses.

Emmanuel A ZavalisAnaïs RameauAnirudh SaraswathulaJoachim VistEwoud SchuitJohn P A Ioannidis

Published in: BMJ open (2024)

Though the relative merits of surgical versus drug interventions are important to know for many diseases, high strength randomised evidence is rare. More randomised trials comparing surgery to drug interventions are needed.

Keyphrases

meta analyses
systematic review
clinical trial
physical activity
open label
study protocol
double blind
minimally invasive
adverse drug
drug induced
coronary artery bypass
surgical site infection