Hydroxychloroquine prescription trends and predictors for excess dosing per recent ophthalmology guidelines.
April M JorgeRonald B MellesYuqing ZhangNa LuSharan K RaiLucy H YoungKaren H CostenbaderRosalind Ramsey-GoldmanS Sam LimJohn M EsdaileAnn E ClarkeM B UrowitzAnca AskanaseCynthia AranowMichelle PetriHyon ChoiPublished in: Arthritis research & therapy (2018)
A substantial proportion of HCQ users in the UK, particularly women, may have excess HCQ dosing per the previous or recent weight-based guidelines despite a modest decline in recent years. Over half of normal-BMI individuals were excess-dosed per the latest guidelines. This implies the potential need to reduce dosing for many patients but also calls for further research to establish unifying evidence-based safe and effective dosing strategies.