BV2-derived extracellular vesicles modulate microglia inflammatory profile, neuronal plasticity, and behavioural performances in late adult mice.

Arianna RinaldiMarta BaliettiElisa PrincipiMariassunta De LucaEleonora De FeliceFrancesca Michela NarcisiLaura VilardoMaria RositoRoberto PiacentiniGiuseppina D'AlessandroIgea D'AgnanoLaura MaggiFiorenzo ContiCristina LimatolaMyriam Catalano

Published in: Brain, behavior, and immunity (2024)

Our data indicate that BV2-derived EVs could represent a resource to slow down age-dependent inflammation in the mouse brain.

Keyphrases

oxidative stress
lps induced
lipopolysaccharide induced
inflammatory response
electronic health record
big data
high fat diet induced
adipose tissue
cerebral ischemia
spinal cord
skeletal muscle