Association of insulin-like growth factor binding protein-7 promoter methylation with esophageal cancer in peripheral blood.

Zehra KayaNecat AlmalıElif Sena SahinSeren DuranGökhan GörgisenCan Ates

Published in: Molecular biology reports (2022)

Our study indicated that promoter unmethylation and mRNA expression of the IGFBP7 promoter in peripheral blood could be different biomarkers for EC. Furthermore, unmethylation of the IGFBP7 promoter in EC patients was associated with reflux and elevated globulin levels. More studies with a larger number of cases is needed to confirm this association.

Keyphrases

peripheral blood
dna methylation
transcription factor
gene expression
end stage renal disease
binding protein
genome wide
newly diagnosed
ejection fraction
chronic kidney disease
peritoneal dialysis
patient reported outcomes
growth hormone