A review of magnetoencephalography use in pediatric epilepsy: an update on best practice.
Hiroshi OtsuboHiroshi OgawaElizabeth PangSimeon M WongGeorge M IbrahimElysa WidjajaPublished in: Expert review of neurotherapeutics (2021)
Introduction: Magnetoencephalography (MEG) is a noninvasive technique that is used for presurgical evaluation of children with drug-resistant epilepsy (DRE).Areas covered: The contributions of MEG for localizing the epileptogenic zone are discussed, in particular in extra-temporal lobe epilepsy and focal cortical dysplasia, which are common in children, as well as in difficult to localize epilepsy such as operculo-insular epilepsy. Further, the authors review current evidence on MEG for mapping eloquent cortex, its performance, application in clinical practice, and potential challenges.Expert opinion: MEG could change the clinical management of children with DRE by directing placement of intracranial electrodes thereby enhancing their yield. With improved identification of a circumscribed epileptogenic zone, MEG could render more patients as suitable candidates for epilepsy surgery and increase utilization of surgery.
Keyphrases
- temporal lobe epilepsy
- drug resistant
- clinical practice
- young adults
- minimally invasive
- end stage renal disease
- multidrug resistant
- resting state
- coronary artery bypass
- chronic kidney disease
- newly diagnosed
- ejection fraction
- primary care
- peritoneal dialysis
- gold nanoparticles
- risk assessment
- quality improvement
- surgical site infection
- atrial fibrillation