Simian retrovirus transmission in rhesus macaques.

Peter NhamBryson HalleyKoen K A Van RompayJeffrey RobertsJoAnn L Yee

Published in: Journal of medical primatology (2024)

Historically, to generate Simian Retrovirus (SRV) positive control materials, we performed in vivo passage by inoculating uninfected rhesus macaques with whole blood from an SRV-1 infected (antibody and PCR positive) macaque. However, recent attempts using this approach have failed. This study reports observations and explores why it has become more difficult to transmit SRV via in vivo passage.

Keyphrases

hiv infected
emergency department
adverse drug
antiretroviral therapy
real time pcr
drug induced