Incidence of elevated creatine phosphokinase between daptomycin alone and concomitant daptomycin and statins: A systematic review and meta-analysis.
Masaru SamuraKeisuke TakadaNaoki HiroseTakenori KurataFumio NagumoSakura KoshiokaJunichi IshiiMasaki UchidaJunki InoueYuki EnokiKazuaki TaguchiKoji TanikawaKazuaki MatsumotoPublished in: British journal of clinical pharmacology (2022)
The combined use of daptomycin and statins were significant risk factors for the incidence of CPK elevation defined as levels ≥ULN or ≥5× ULN and rhabdomyolysis.