Relationships of Glucose, GLP-1, and Insulin Secretion With Gastric Emptying After a 75-g Glucose Load in Type 2 Diabetes.
Ryan Joseph JallehTongzhi WuKaren Louise JonesChristopher K RaynerMichael HorowitzChristopher K RaynerPublished in: The Journal of clinical endocrinology and metabolism (2022)
In T2D, while insulin secretion is the dominant determinant of the 120-minute plasma glucose, GE also correlates. Given the relevance to interpreting the results of an oral glucose tolerance test, this relationship should be evaluated further. There appears to be no direct effect of GE on either GLP-1 or insulin secretion.