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Dimethyl fumarate ameliorates graft-versus-host disease by inhibiting T-cell metabolism and immune responses through a reactive oxygen species-dependent mechanism.

Kiyomi MashimaKazuya SatoTakashi IkedaJunko IzawaNorihito TakayamaHiroko HayakawaShin-Ichiro KawaguchiHirofumi NakanoTakashi NagayamaKento UminoKaoru MoritaKaoru TominagaHitoshi EndoYoshinobu Kanda
Published in: British journal of haematology (2022)
Keyphrases
  • reactive oxygen species
  • immune response
  • signaling pathway
  • mouse model
  • toll like receptor
  • dendritic cells